Typically Harmless Virus May Trigger Celiac Disease
A usually harmless virus may play a role in triggering celiac disease, a new study in mice suggests.
The researchers found that, among mice that were genetically engineered predisposed to celiac disease, those that were infected with a virus called reovirus were more likely to have an immune response against gluten than mice not infected with a reovirus. This immune response is similar to what’s seen in people with the condition.
Although human infections with reoviruses are common, the viruses don’t cause symptoms in people. But the study also found that patients with celiac disease did have higher levels of antibodies against reovirus, compared to people without the condition.